Polyphron

Summary Updated Sep 18, 2026

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Location New York, NY
Latest Stage Seed
Total Raised $20M (2026 seed)

Investors

Quiet Capital seed (2026)

Founders

Matt Osman CEO & Co-Founder
Fabio Boniolo CSO & Co-Founder
Vinh Q. Tran Chief AI Scientist & Co-Founder
George Pilitsis COO & Co-Founder

About

Polyphron is a New York–based biotech developing artificial human biology by combining physical tissue manufacturing with AI simulation, producing donor-diverse human tissues that serve as a verification substrate for testing biological interventions at scale 12. The company’s stated aim is to close the gap between AI-generated interventions and the slower biology required to validate them 1. Its founding team comes out of Google DeepMind, the Broad Institute and Harvard Medical School, Ginkgo Bioworks, and prior AI startup exits 1.

Funding History

Date Round Amount Lead Co-investors
2026-09-17 Seed $20M Quiet Capital Gradient, Haystack, Compound 234

What Investors Say

No independently sourced investor quotes beyond announcement boilerplate at time of profile creation.

What Founders Say

No independently sourced founder testimonials found at time of profile creation.

Sources


  1. Polyphron company website, “Home,” accessed September 18, 2026. https://polyphron.com/

  2. AlleyWatch, “The AlleyWatch Startup Daily Funding Report: 9/17/2026,” September 17, 2026. https://alleywatch.com/2026/09/the-alleywatch-startup-daily-funding-report-9-17-2026/

  3. Axios Pro Rata (Dan Primack), deal listing for Polyphron $20M seed, September 17, 2026. https://www.axios.com/newsletters/axios-pro-rata

  4. Quiet Capital portfolio page, accessed September 18, 2026. https://quiet.com/portfolio/ — Polyphron is listed among Quiet Capital’s active portfolio companies, confirming the lead investor relationship.